Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1345 | Pituitary Basic | ICEECE2012

Increased interleukin 22 circulating levels in patients with tumors involving the hypothalamic-pituitary region

Cotta O. , Gangemi S. , Ferrau F. , Saitta S. , Torre M. , Puglisi S. , Trimarchi F. , Cannavo S.

Introduction: Cytokines have been suggested to be involved in modulating anti-tumor responses and promoting tumor growth. Some studies have indicated that cytokines could also be involved in the pathogenesis of pituitary tumors. Th17 cells, characterized by expression of several cytokines as interleukin 22 (IL 22), might have a role in tumor immune-surveillance. IL-22 is a cytokine involved in the modulation of tissue responses during inflammation and, through activation of St...